Posted by notfred on April 5, 2007, at 12:31:14
In reply to Re: Lamictal made me very sick » Phillipa, posted by polarbear206 on April 5, 2007, at 12:20:35
"SJS is the life threating rash that can ultimately cause a severe systemic reaction and progress to organ failure. There is a 1% chance of this happening. I got a rash when I first started Lamictal, but it went away. I am blonde and have fair skin. More prone to rashes."
The rate is .08% for those taking Lamictal (.8 in 1000) which is 2 orders of magnitude less than 1 %.
It is not even 1% for those taking Lamictal and other anti-sezure meds or with your childern.
Here are the facts from the monograph:SERIOUS RASHES REQUIRING HOSPITALIZATION AND DISCONTINUATION OF TREATMENT HAVE BEEN REPORTED IN ASSOCIATION WITH THE USE OF LAMICTAL. THE INCIDENCE OF THESE RASHES, WHICH HAVE INCLUDED
STEVENS-JOHNSON SYNDROME, IS APPROXIMATELY 0.8% (8 PER 1,000) IN PEDIATRIC PATIENTS (AGE <16 YEARS) RECEIVING LAMICTAL AS ADJUNCTIVE THERAPY FOR EPILEPSY AND 0.3% (3 PER 1,000) IN ADULTS ON
ADJUNCTIVE THERAPY FOR EPILEPSY. IN CLINICAL TRIALS OF BIPOLAR AND OTHER MOOD DISORDERS, ***THE RATE OF SERIOUS RASH WAS 0.08% (0.8 PER
1,000) IN ADULT PATIENTS RECEIVING LAMICTAL AS INITIAL MONOTHERAPY*** AND 0.13% (1.3 PER 1,000) IN ADULT PATIENTS RECEIVING LAMICTAL AS ADJUNCTIVE THERAPY.
poster:notfred
thread:747160
URL: http://www.dr-bob.org/babble/20070402/msgs/747221.html