Posted by Ines on April 2, 2007, at 12:24:58
In reply to Re: Reboxetine succes !!!!!/Similar meds, posted by Viking on April 2, 2007, at 1:33:07
Thanks for posting a success story, they're nice to read! I'm really glad you found something that works for you- and it give the rest of us motivation to keep trying.
I'm not sure I agree with you that MAOIs have been the drug of choice for atypical depression due to their effect on noradrenaline (norepinephrine) though. As far as the older drugs go, it is the tricyclics that tend to concentrate on noradrenaline (along with serotonin). MAOIs increase serotonin, noradrenaline and dopamine, and noone really knows why they seem to work better for atypicals. As far as I'm aware reboxetine is considered more similar to a tricyclic than to a MAOI (although different from both obviously because it is so selective and is a reuptake inhibitor).
I have pretty much the same symptoms you report (with the addtition of some ocd symptoms) and reboxetine made me get quite a bit worse, even after the dose was reduced to 4 mg. It increased my anxiety to an unbearable level and gave me wild mood swings and frequent suicide ideation. This is not to discourage anyone- I'm sure reboxetine will work great for many people, but not all atypicals.
Oh, in response to stargazer's question, reboxetine wasn't approved in the US, noone quite knows why.
I hope rebox continues doing the trick for you Viking!