Posted by Jedi on March 22, 2007, at 2:18:28
In reply to Need some feed back guys come on, posted by willyee on March 21, 2007, at 18:05:41
Hi,
Certain drugs in the opiod family will produce serotonin toxicity when mixed with a MAOI. Others do not effect serotonin and thus pose no problem. I have take codeine with Nardil with no reaction at all. Be careful with this though, because even in Canada, where codeine is sold over the counter, other meds are mixed with it which will often times cause serious problems."We can reliably predict that only those opiates that are significant serotonin reuptake inhibitors (or releasers) will precipitate serotonin toxicity with MAOIs.
In summary: Morphine, codeine, oxycodone, buprenorphine do not precipitate serotonin toxicity with monoamine oxidase inhibitors. Pethidine (meperidine), tramadol, methadone and fentanyl, propoxyphene, dextromethorphan, are borderline. They are weakly serotonergic and some may precipitate serotonin toxicity which must be assumed to be dose dependant."
©Dr Ken Gillman MRC Psych - PsychoTropical Research®
http://www.psychotropical.com/8_st_maois_opiate_analgesics.shtmlI saw nothing in the prescribing information that would keep you from using Suboxone with Parnate. (Double and Triple Check!)
US Prescribing Information
www.suboxone.com/patients/pi/Where did you find a doctor who will prescribe buprenorphine for depression?
Good Luck,
Jedi> Ok so after lots of reading,ive since come to the conclusion that i want to try the suboxone/parnate combo.
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> Reason being not many things are helping in augmentation of parnate,not to many docs are willing to keep trying,and im simply sick of taking these drugs that just set me back.
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> I do have a handful that work well with parnate however no where near where i need it to.
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> I have searched and dont see a substitute to parnate for my primary drug,the old nardil would have been one,but im simply not prepared to switch to this new one.
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> Also im hoping suboxone can help with the second part of my illness which i believe i unknowingly created,which is the obession that i need to keep trying drugs,ive seen lots of users in archives speak of the two togther.
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> Heres my question,i personaly for me know without a doubt that ultram is not safe with parnate,for me its a direct no no,my concern is arent ultram and suboxone very similiar in the opoid family,and if so,would suboxone also like ultram be extremly contradicted,im hoping now as i already started the process.
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> Please help,and please as nice as i can ask in text dont address the question with answers other than the actual question,i already started,so i need to know this,not any other options on different meds etc.
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> Id be very disappointed if this goes unanswered,i know someone out there has some input please share.
poster:Jedi
thread:742970
URL: http://www.dr-bob.org/babble/20070320/msgs/743099.html