Posted by yxibow on March 18, 2007, at 0:02:31
In reply to Re: Worst side-effect you've had from a med?, posted by Declan on March 17, 2007, at 17:40:55
> I had a dystonic reaction from Torecan, a phenothiazine type anti-nauseant.
>
> I was fortunate enough to know what a dystonic reaction was and to have diazepam and an anticholinergic drug handy.
>
> Tearing yourself apart.Torecan is somewhat similar to Compazine.
I had a highly akathisic reaction to Compazine due to high fever and instoppable vomiting.
Benadryl stopped it, unfortunately they didn't reinject it before I left the hospital and I could barely tell the driver how to get home because it affected my mental state too.
Its a hard decision what to use to manage what can be fairly unstoppable vomiting in an ER setting, but antiemetic phenothiazines are among the harshest neuroleptic categorized substances.
There are more modern medicines available today, such as the 5HT3 blockades. They cost $25 a dose, and I'm not sure if they would stop a runaway episode of vomiting as fast as a phenothiazine or how many doses it would take.
Of course, Benadryl itself also has anti-emetic qualities.
There is Tigan, which is less harsh than Compazine and also is an anti-nausea agent. It carries considerably less movement risks. I don't know its usefulness in the same situation, as well.
poster:yxibow
thread:741810
URL: http://www.dr-bob.org/babble/20070314/msgs/741898.html