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Re: Stimulants-Please be careful! » yxibow

Posted by Reggie BoStar on February 2, 2007, at 8:53:39

In reply to Re: Stimulants-Please be careful! » Reggie BoStar, posted by yxibow on February 1, 2007, at 20:07:30

Actually, yxibow, Benzos are only used during Alcohol detox treatments. Once the detox treatments are complete, Benzos are contraindicated. This is why I, along with the vast majority of substance abusers, are not prescribed Benzos after detox treatment is done. Since I never specified why Benzos were contraindicated for me, you were premature in your assumption that I meant detox as well as post-detox recovery.

Also, I never said anything about using Buspar as an antipsychotic. I referred to it as a treatment for GAD, which you verified by describing it as an anxiolytic. In this context, its lack of success as an antipsychotic is irrelevant. I'm not sure why you mentioned this at all.

As far as the 1/3 response, that depends on whose study you choose to believe. Among those which include its use as treatment for dual diagnosis (anxiety and alcoholism) conditions as well as GAD, these studies show a higher response:

Tollefson GD, Montague-Clouse J, Tollefson SL. Treatment of comorbid generalized anxiety in a recently detoxified alcoholic population with a selective serotonergic drug (buspirone). J Clin Psychopharmacol. 1992;12:19-26.

Kranzler HR, Burleson JA, Del Boca FK, et al. Buspirone treatment of anxious alcoholics. A placebo-controlled trial. Arch Gen Psychiatry. 1994;51:720-731.

J Clin Psychiatry. 1990 Sep;51 Suppl:40-5. A double-blind, controlled trial in primary care patients with generalized anxiety: a comparison between buspirone and oxazepam. Strand M, Hetta J, Rosen A, Sorensen S, Malmstrom R, Fabian C, Marits K, Vetterskog K, Liljestrand AG, Hegen C. Primary Care Center, Enkoping, Sweden.

I would be very much interested in knowing which studies you are citing when you report a 1/3 response rate to Buspar.

Thanks,
Reggie BoStar


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