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Re: Why is valium relatively unpopular? » yxibow

Posted by Quintal on January 31, 2007, at 12:52:35

In reply to Re: Why is valium relatively unpopular? » saturn, posted by yxibow on January 31, 2007, at 1:41:00

Restoril (temazepam) is a minor metabolite of diazepam and has a half-life of around 8 hours. The metabolite responsible for diazepam's long half-life is nordiazepam:
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Diazepam is a muscle relaxant and antianxiety drug. Peak blood levels are achieved within an hour after oral dose. Half-life in adults is 21-37 hours. The major metabolite (nordiazepam) has a half-life in adults of 50-99 hours. It is the major metabolite also of clorazepate and prazepam. Minor active metabolites of diazepam are temazepam (3-hydroxydiazepam) and oxazepam (3-hydroxy-N-diazepam).
http://www.labcorp.com/datasets/labcorp/html/chapter/mono/td033900.htm
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Q


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