Lithium increases glucocorticoid receptor

Posted by dessbee on January 25, 2007, at 9:09:34

Chronic administration of LiCl increased the expression of glucocorticoid receptor (GR) mRNA in the hippocampus and paraventricular nucleus (PVN)
Since the hippocampus and PVN mediate negative feedback regulation of the HPA axis, an increased expression of GR mRNA in these regions may normalize HPA axis activity in mood disorders.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11070198&dopt=Abstract

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Lithium increases glucocorticoid receptor dessbee 1/25/07
Re: Lithium increases glucocorticoid receptor Jimmyboy 1/29/07

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