Posted by blueberry1 on January 21, 2007, at 9:57:41
In reply to Adrafinil - anyone with good or bad experience, posted by meAgain on January 20, 2007, at 21:44:24
I have toyed with adrafinil several times over the years. And I keep trying it. By itself I do not like it. It is one of those meds that I think seems best as an ingredient in a combination that pulls everything together. It perked up prozac nicely and I stayed on that combo for a couple years. It added energy, motivation, and interest. On this page is a thread by Jimmyboy who is having a successful time with adrafinil.
Just my experience alone, but it seems to work best in combo with a ssri.
What happens when I take it. Immediate energy and mood elevation on day 1. Energy and concentration boost continues, but mood elevation disappears after that. Then after a few weeks, it 'kicks in'. But without a ssri, it just doesn't work right. Too much restlessness, obsessiveness, uptightness.
Adrafinil breaks down in the body to provigil. So it is a poor man's version of provigil. But the two are not directly comparable. Some people prefer one over the other.
I think the doses given on the instructions are too high. I found best results in the 300mg to 600mg range. 300mg was my favorite dose. I have tried once daily dosing versus multiple dosing and I like multiple dosing better. I split a pill in halves or quarters for that.
Like I said, by itself I do not like it at all. But with a ssri it is a completely different positive way. Don't know why it changes personality so drastically like that.
By itself it does offer one benefit for me. It can lift me from the depths of despair pretty quickly on the first day. After that, not much good. It really needs a ssri as a partner. But that is just my experience and will not be the same as someone else. You know how mileage varies.
poster:blueberry1
thread:724632
URL: http://www.dr-bob.org/babble/20070119/msgs/724746.html