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Re: 5-ht1b autoreceptors question Linkadge

Posted by Denise190466 on January 10, 2007, at 14:22:34

In reply to 5-ht1b autoreceptors in depressed mice, posted by linkadge on December 26, 2006, at 17:25:08

How does this study relate to the one on P11 where they found that increasing this protein also increased the number of 5HT1B receptors on the cell surface.

Doesn't this study contradict the one on Pll. if the overactivy of 5HT1B receptors contributes to depression then wouldn't have more than one of them on the cell surface contribute to it as well. I mean wouldn't having lots of them equate to having an overactive 5HT1B system?

Also you mentioned drugs which are in the pipeline which might test this theory, which drugs are they and how soon will they be out?

How soon do you think it will be before they are manipulating genes in order to combat depression?


Denise


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poster:Denise190466 thread:716561
URL: http://www.dr-bob.org/babble/20070107/msgs/721089.html