Posted by Tomatheus on December 25, 2006, at 15:43:10
In reply to Re: Nardil+Bupropion, posted by tecknohed on December 25, 2006, at 9:35:36
Tecknohed,
Thank you for your detailed reply and for the update on your trial with Nardil and bupropion. It's wonderful to hear that your response has continued to improve, and I hope that the improvement continues.
See below for my responses to specific portions of your post...
> As for mood stabilizers, I try to avoid them. I've tried one (forgot which one) & it just dampened my mood. I cant live like that.
Personally, I tend to avoid mood stabilizers these days, as well. I probably shouldn't keep repeating the details of my experience with lithium because others certainly have more positive experiences with it, but as you know, lithium monotherapy had an extremely disturbing effect on me -- an effect that still has not completely gone away. I also took Zyprexa at one point for its "mood stabilizing" effects and basically lost what little capacity that I had to think clearly and coherently prior to taking it. I pretty much felt like a complete zombie. Fortunately, it was obvious that I wasn't responding favorably to Zyprexa and wasn't going to experience any kind of therapeutic benefit from it at any point, so I didn't stay on it for too long. At least Zyprexa's effects went away after I stopped taking it, unlike the effects of lithium.
I still haven't ruled out the possibility of trying Lamictal at some point in the future if I don't end up getting a sustained response out of the combo that I'm on now. At the same time, I'm not big on the idea of taking any sodium channel-blocking drugs -- even something like Lamictal that also seems to have some antidepressant properties (which probably result from its ability to reduce the release of glutamate).
But generally speaking, I too have tended to avoid mood stabilizers as of late. I suspect that my affective disorder is essentially a double depression of sorts that needs to be treated with two different types of antidepressants in order to go into anything that even remotely resembles a sustained period of remission. The antimanic effects of most of the so-called mood stabilizing drugs on the market today are the last thing that I need to help restore and maintain my functionality.
> Overall much more positive - great!
That's definitely good news. It couldn't come at a better time, either. I'll continue to keep my fingers crossed in hopes that you continue to receive sustained benefits from the Nardil-bupropion combo.
> Oh, Merry Christmas to all!
Same to you (and to all)!
Tomatheus
poster:Tomatheus
thread:712640
URL: http://www.dr-bob.org/babble/20061224/msgs/716341.html