Posted by Tomatheus on December 18, 2006, at 0:29:22
In reply to Re: Nardil + nortriptyline is working. » Tomatheus, posted by SLS on December 16, 2006, at 20:06:40
> > I'm wondering, did you notice any significant AD effect from Nardil at 60 mg,
>
> Yes, but it plateaued and dissipated somewhat.Shoot. I was afraid of that. I had a similar response to the film-coated Australian Nardil at 75 mg/day before I started preparing the tablets in enteric capsules like Michael Bell was doing for a while with the U.S. Nardil (to make a long story short, I then went into complete remission for about a month, lost my response completely and noticed an abrupt increase in side effects after receiving a Nardil bottle without any silica gel inside of it, tried the enteric-capsule approach with the U.S. Nardil, experienced a consistent-but-only partial response for about two months, had severe panic attacks shortly after receiving what was probably a "bad lot" of Nardil from my pharmacy, and finally gave up on the medication entirely).
At 60 mg/day of the film-coated Australian Nardil, my response also followed the same type of pattern (with the plateau and subsequent dissipation), but in my case, the AD effect was hardly noticeable. I had to get up to 75 mg/day before I started feeling noticeably improved.
Of course, just because I couldn't get a lasting response (anything longer than about two weeks) from film-coated Nardil at 60 or 75 mg/day doesn't mean that you won't from 75 or 90 mg/day of the medication. Even though you only experienced short-term relief at 60 mg/day, maybe the effects of the nortriptyline, Lamictal, Topamax, and Abilify that you're taking will somehow mix well with the effects of 75 mg/day of Nardil to produce a nice long-term effect. So, I think there's still some reason to be optimistic, despite the fact that the dissipation of Nardil's AD effect that you experienced at 60 mg/day doesn't seem to be a good sign.
> > P.S. I still own you a Nardil-related post from ages ago. I started writing it when I had a small trace of energy, and then I fell back into my "normal" state of extreme psychomotor retardation and couldn't add a word to it. If you're still interested, I can finish it up.
>
> When you have the energy, I'd be interested. However, it wouldn't be important enough for you to struggle over it right now. I'm sorry to hear that you are so severely ill. Psychomotor retardation is a reliable index of illness severity. I suffer from it greatly.I've actually been feeling ok for most of the past week on a combination of the Goldshield Parnate (20 mg/day) and SAM-e (200 mg/day). I don't feel quite as upbeat as I did when I was in remission on 75 mg/day of my partially homemade enteric version of the Australian Nardil, and my thinking still feels somewhat clouded a lot of the time due to what I think is probably some residual fatigue. But I've been more or less functional for several days now, and I've actually been able to keep my sleep-wake pattern from falling out of whack, which is a lot more than I can usually say. I have some reason to believe that the right dose of SAM-e (hopefully the 200 mg/day) may allow me to get a lasting response from the Goldshield Parnate instead of the 2-3 day tease that I usually get from it, but it's far too early for me to declare victory. Time will tell what my long-term response will be.
At any rate, if the partial response that I'm experiencing right now continues for at least another few days, I'll get that message of mine finished up when I get the chance.
Tomatheus
poster:Tomatheus
thread:714163
URL: http://www.dr-bob.org/babble/20061217/msgs/714709.html