Psycho-Babble Medication | about biological treatments | Framed
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Hey man, don't knock accidental discovery linkadge

Posted by madeline on November 4, 2006, at 16:55:35

In reply to Re: My first one worked..., posted by linkadge on November 4, 2006, at 13:56:06

Penicillin immediately comes to mind. Then coumadin, then too many come to mind to list.

About 10 years ago "rational drug design" was all the rage. It failed miserably.

Then massive screenings (still ongoing).

Basically, I think it is very safe to say that we know very little about what we are doing when it comes to drug discovery and development.

While there are a few instances where knowing the fundamental mechanism of disease progression has led to successful therapy (read gleevec), overall it's still a big crap shoot.

It's just like what billy joel said "some of the most creative things I have ever done have been my mistakes"

So, take it easy on us, we are doing the best we can.

Maddie


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Psycho-Babble Medication | Framed

poster:madeline thread:700174
URL: http://www.dr-bob.org/babble/20061104/msgs/700365.html