Posted by yxibow on November 1, 2006, at 13:44:05
In reply to SEROQUEL...monotherapy for Depression?, posted by stargazer on November 1, 2006, at 11:32:58
> My doctor is telling me he is treating some patients with seroquel alone successfully. I knew it was just approved for BP but wasn't familiar with treating MDD with it.
>
> I know it's more the symptoms which are treated than the diagnosis so I guess this makes sense, right?
>
> Anyone having luck with this? What dosage? How long?
>
> I started seroquel 25 mg on 10/30. Tonight I'll increase to 50 mg. I'm also on Cymbalta 30 mg (couldn't go any higher than 30 d/t headaches)since I had already been on that but I think the plan is to stop that (or not) down the road.
>
> SG
Its best as augmentative therapy for depression as augmentative for anxiety disorders but as I've noted, it, like Remeron, forms a serotonin blockade on certain key receptors, in a way that other antidepressants are normally reuptake inhibitors.So one could use it as monotherapy but I wouldn't use personally any neuroleptic until I've tried the usual cast of SSRI/SSNRIs/TCAs (and possibly MAOIs -- gasp).
Augmentative the dose would be lower because its synergistic with another medication, as monotherapy the dose I am only surmising would have to be much higher subjecting one to greater EPS.
The tradeoff is that as an offlabel antidepressant it works much faster, things like Zyprexa, Seroquel, etc, within a week can lift spirits.
-- tidings
Jay
poster:yxibow
thread:699566
URL: http://www.dr-bob.org/babble/20061028/msgs/699594.html