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Re: nicotine. oleamide and post-synaptic 5ht1a Rs

Posted by linkadge on November 1, 2006, at 12:57:00

In reply to nicotine. oleamide and post-synaptic 5ht1a Rs, posted by iforgotmypassword on November 1, 2006, at 10:21:28

Oleamides are fatty acids. I think they are produced in the body from oleic acid. I think all of them potentiate 5-ht1a. Some of them are 5-ht2a agonists, and some of them are 5-ht2a antagonists.

Oleamide is metabolized by FAAH, fatty acid anandamide hyroxylase (?). There are FAAH inhibitors in the pipelines for depression and anxiety disorders.

Consuming more oleic acid may result in more oleamides in the brain.

Linkadge


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URL: http://www.dr-bob.org/babble/20061028/msgs/699581.html