Posted by ronaldo on October 29, 2006, at 15:24:32
In reply to Re: High dose benzo usage, posted by dbc on October 27, 2006, at 23:31:04
> Well the good news is your brain is just going to stop encoding memories long before you get even remotely close to the LD50. People are prescribed up to 10mg of xanax for panic disorder and some are prescribed a hell of alot more. Combining the booze and benzos is where you get into trouble though, i'd seriously cut down on that combination.
>
> 5mg a day was the highest dose i ever took with klonopin and i was lucky if i could tie my boots at that point.What does LD50 mean?
"LD stands for "Lethal Dose". LD50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD50 is one way to measure the short-term poisoning potential (acute toxicity) of a material.
Toxicologists can use many kinds of animals but most often testing is done with rats and mice. It is usually expressed as the amount of chemical administered (e.g., milligrams) per 100 grams (for smaller animals) or per kilogram (for bigger test subjects) of the body weight of the test animal. The LD50 can be found for any route of entry or administration but dermal (applied to the skin) and oral (given by mouth) administration methods are the most common."
http://www.ccohs.ca/oshanswers/chemicals/ld50.html
So what is the LD50 for a 80kg man? Where would one find this information? On the pamphlet inside the little cardboard box that the pills came in? Never seen it myself.
...Alan
poster:ronaldo
thread:698250
URL: http://www.dr-bob.org/babble/20061028/msgs/698773.html