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Re: Long term Olanzapine for BP....any comments?

Posted by SLS on October 29, 2006, at 8:56:04

In reply to Long term Olanzapine for BP....any comments?, posted by ronaldo on October 29, 2006, at 7:55:53

Therapeutically, olanzapine (Zyprexa) can work miracles with a relatively low risk of EPS and TD. However, it can wreak havoc with glucose dynamics and triglycerides, and cause weight gain. If you monitor these things carefully and don't run into problems, you might not need to search for another drug. I would just mention that aripiprazole (Abilify) offers much of the same therapeutic benefit as olanzapine against negative symptoms and is without these metabolic drawbacks. It sometimes produces anxiety and insomnia as startup side effects during the first few weeks, but these usually disappear. It can be a remarkably clean drug.


- Scott

 

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poster:SLS thread:698653
URL: http://www.dr-bob.org/babble/20061028/msgs/698661.html