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Re: Memantine/Namenda CBT question

Posted by chess on September 23, 2006, at 20:41:04

In reply to Memantine/Namenda CBT question, posted by chess on September 22, 2006, at 10:41:17

I think I have a good guess about it.
Memantine only kicks in when there's an excessive amount of glutamate activity, so maybe "excessive" glutamate activity interferes with learning as much as "insufficient" glutamate activity interferes with learning (remember d-cycloserine is an glutamate receptor agonist), and thus memantine allows for normal glutamate activity and the normal learning that leads to extinction.


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URL: http://www.dr-bob.org/babble/20060919/msgs/688538.html