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Re: sleep paralysis » zeugma

Posted by yxibow on September 22, 2006, at 19:50:52

In reply to Re: sleep paralysis » tizza, posted by zeugma on September 22, 2006, at 18:33:50

> Most srimulants (Ritalin, amphetamines) also have anticataplectic activity- albeit less than TCA's or Xyrem. Provigil has none. When I took a high dose of Ritalin with nortriptyline, I experienced no sleep paralysis whatsoever. I have to be very careful with Provigil, because it can exacerbate the cataplexy-related symptoms (whether it directly provokes them through a mixed antagonist/agonist action at alpha-1 receptors, or reduces the plasma levels of anticataplectic drugs through enzyme induction, or simply reduces sleep which itself causes increased cataplexy, is unclear. What is not unclear is that it is not helpful at all for cataplexy-related symptoms, such as sleep paralysis.)
>
> Strattera is very effective at blocking sleep paralysis. If you are in the UK, reboxetine might be a good thing to try.
>
>
> -z


Actually Provigil has been used for narcolepsy but I was just listing it because its less harsh -- yes, phenylamines like amphetamines are used as well; SSRIs are used, a number of substances have been tested against various forms of this sleep disturbance.

 

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