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Re: Emsam: constant dosing? Jost

Posted by WeeWilly on September 21, 2006, at 22:55:11

In reply to Re: Emsam: constant dosing?, posted by Jost on September 21, 2006, at 21:28:07

> My pdoc just told me that the company making Emsam doesn't promise constant, time-release absorption of the drug from the patch.
>
> More likely, absorption varies considerably. First of all, it varies from person to person. But also, it varies within 24 hours.
>
> The most the company claims is that you'll get about 6 mg (actually probably between 4-6 mg) from the 6 mg patch every twenty-four hours. But there's a good chance, for example that the highest absorption could be at the beginning right after application of the patch.
>
> I'm not sure this matter so much, under good conditions, as long as you replace the patch every 24 hours.
>
> Jost

Interesting. I have been on Emsam for about 1 month. 2 weeks or so on 12mg. I have been leaving each patch on for 48 hrs. I wear 2 patches. So far my response has been disapointing. Seeing my Pdoc 9/26 tues and I am leaning toward discontinuing Emsam and maybe trying Marplan. Many years ago when I first tried Parnate my response was complete within a 1/2 hour it remained great for 3 months then abruptly quit. Increased the dose to 100 mg's with no luck. Every year since then I have returned to Parnate for 3 months per year. Usually the response is quick and last 3 months. Last spring it was not quite so good, likely because of my being on Nardil a few months before the parnate. Nardil was not as effecatious as Parnate. It also lost its effectiveness after 3 months. I sure thought I would stumble onto a treatment long ago but providence has'nt provided that. At one time I responded great to sleep deprivation, but not anymore. If you knew my existence you would not believe how strange it is. Oh well, thems the cards I have been dealt. I often wonder if I am playing them the best possible way. I think so. Of course if I did'nt have the disableing symptoms of this disorder I could be more organized in recording factors in my condition and analyzing the best course of action then do it. I would like to hook up with an influential research scientist at NIMH or similar place. I think I have unique information that I have accumulated that would illuminate disorders such as mine. I'm running on here so I'll just wish you all the best fortune. Thanks for listening.


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poster:WeeWilly thread:630549
URL: http://www.dr-bob.org/babble/20060919/msgs/688047.html