Posted by SLS on September 4, 2006, at 21:18:31
In reply to Re: Geodon - - depression better - anxiety worse., posted by SLS on September 4, 2006, at 21:07:16
> > Hi.
> >
> > I wasn't aware that Geodon was a NE alpha-2 antagonist.
>
> I see from the PDSP database that Geodon has a modest affinity for NE alpha-2a/b/c receptors, so your theory as to why you are experiencing anxiety is quite plausible. Clonidine, a NE alpha-2 agonist used to treat hypertension, was used as the hot ligand to test for receptor occupancy in the database. This drug might act as an antidote to reduce your anxiety if Geodon is worth continuing for its antidepressant effect.One thing, though. Despite the occasional use of clonodine as a sedative or anxiolytic, it can be depressogenic.
- Scott
poster:SLS
thread:683055
URL: http://www.dr-bob.org/babble/20060901/msgs/683168.html