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Re: Lyrica (pregabalin) - Side Effects ?

Posted by Cairo on September 3, 2006, at 9:49:53

In reply to Re: Lyrica (pregabalin) - Side Effects ? » ed_uk, posted by SLS on September 1, 2006, at 15:29:08

My only suggestion is to ramp up Lyrica slowly. I had extreme unsteadiness, spaciness and almost a euphoric feeling when I tried to increase the dose quickly. I was told to wait one week before a dose increase, but I'm pretty sensitive to meds.

I can't take Lyrica during the day, however, because of the unsteadiness and feelings of depersonalization. I do experience some anti-anxiety effect. Muscle relaxation, which is the main reason I started it, poops out pretty quickly for me. This also happened with Neurontin.

I definitely like it as an adjunct to trazodone for sleep. A repeat sleep study with me on 150mg Lyrica and 50mg trazodone showed a great sleep profile.

As for Fibromyalgia pain, much of my pain comes from muscle tightness and trigger points. Lyrica helps some initially, then goes away, as I've said. But I know of someone who says it has made all the difference in the world for her FMS pain. I have anxiety/panic issues going on now, so I may be a different subset of FMS.

Good luck.

Cairo


> I started Lyrica last night with a single 25mg dose. I will take my second 25mg dose tonight. I slept well. Today has been better than the several days previous. It is difficult to assess the contribution of Lyrica to this. I did feel something different early in the day, though. It was not unpleasant. I might move up to 50mg tomorrow.
>
>
> - Scott


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