Posted by WeeWilly on August 18, 2006, at 14:33:09
Since the modes of actions of all pycho-active medications are unknown, treatment is literally a shot in the dark. I have felt for many many years that it was very unfortunate that the initial developments in depressive disorder research focused on monoamines. It has not only given us to many me too medications but also me too research fixated on monoaminergic theories.
I will be 48 yrs old in another month and have been battalling depressive like symptoms my whole life. From changes in my symptoms begining back when I was about 13 or so, made me suspect a problem in my endocrine system was at the core of my disorder. As time has gone on I have tried so many treatments. Most have been various AD's and combinations. Tried some steroids and endocrine treatments. Like probably most of you, I have followed developments in research. Slowly I have seen a turn away from the fixation on monoaminergic theories as the be all and end all of mood disorders.
Getting back to modes of action and their help in developing a plan of treatment. If they were known it would help in treatment planning and development of better treatments etc. .
Currently I am trying Rozerem. Their seems to be evidence that it can advance circadian rythyms and also lower testosterone, who knows what else?
Do you think I am off base in my ideas? Best wishes.
poster:WeeWilly
thread:677804
URL: http://www.dr-bob.org/babble/20060818/msgs/677804.html