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Re: Sibutramine (Meridia) - Day 9 » SLS

Posted by ed_uk on August 17, 2006, at 16:43:46

In reply to Re: Sibutramine (Meridia) - Day 9 » ed_uk, posted by SLS on August 15, 2006, at 15:28:40

Hi Scott

>Right now, it is difficult to say whether or not it is still helping....

I was wondering whether the side effects of fatigue and breathlessness are symptoms of metabolic acidosis. Metabolic acidosis is common with Topamax because it's a carbonic anhydrase inhibitor. Your doc might do a blood test.

>What adverse effects might you expect from this combination?

Perhaps too much NE reuptake inhibition is bad for depression? Perhaps this is the problem with reboxetine, and why too high a dose of nortriptyline might be ineffective.

Ed


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