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Re: Interesting finding. Is it correct?

Posted by silvercoin on August 16, 2006, at 8:37:21

In reply to Interesting finding. Is it correct?, posted by janeB on August 15, 2006, at 22:38:38

> I never heard that prozac was derived from diphenhydramine! So if prozac is supposed to be energizing why is it making me so tired? I found this possible explanation. Benadryl knocks me out. Does Benadryl=Prozac?
>
> http://en.wikipedia.org/wiki/Fluoxetine
> "Fluoxetine was derived from diphenhydramine, an antihistamine found to inhibit reuptake of the neurotransmitter serotonin.
>
> Compared to other popular selective serotonin reuptake inhibitors (SSRIs), fluoxetine has a strong energizing effect."
>
> If prozac doesn't energize me what will?
> Jane


The structures are relatively similar in the grand scheme of things, but probably not so much that you can associate adverse effects of one drug with the other. Several of the tricyclics have more similar structures than these two drugs but differ widely in their side effects. I personally find Benadryl to make me drowsy, but Prozac is almost unbearably activating.

Todd


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URL: http://www.dr-bob.org/babble/20060810/msgs/677016.html