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Re: couldn't have said it better myself

Posted by SLS on July 12, 2006, at 6:14:48

In reply to Re: couldn't have said it better myself » linkadge, posted by SLS on July 12, 2006, at 5:49:52

> > >In my opinion, the real response to a drug will >occur whether or not a placebo is being >swallowed by the patient in the next room
> >
> > Allong the same lines, a true responce to a placebo will occur whether or not an active drug is being swallowed by the patient in the next room.
> >
> > Linkadge
>
> Precisely. There is no need to have a placebo control for every investigation devised by man. The phenomenology of the placebo response is well quantized. It makes no sense to waste thousands of lives in the STAR*D protocol to test algorithms for drugs that have already been separated from placebo in previous trials.

Here is an example of a study group smart enough to use the historical records of previous placebo-controlled investigations as comparators for their own three-tier antidepressant remission protocol. It seems to echo the STAR*D findings.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=15960558&query_hl=1&itool=pubmed_docsum


- Scott

 

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