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Re: Medication statistics? Best medications?

Posted by SLS on July 12, 2006, at 5:58:26

In reply to Re: Medication statistics? Best medications? linkadge, posted by Jakeman on July 12, 2006, at 2:14:31

> > I think it depends on the type of depression. I think that there is growing suspicion that the TCA's were/are more effective for certain types of depression than the SSRIs.
> >
> > A lot of people think moclobemide doesn't work too well.
> >
> > I think some are likely better than others, I wouldn't know how to go about rating them though.
> >
> >
> > Linkadge
> >
> >
>
> Most people can't tolerate the side effects of tca's like Elavil and Pamelor.

As with other drugs, I think the side effects of the tricyclics can be minimized if the initial doses are low and the titration gradual. This has been my experience. Desipramine (Norpramin) and nortriptyline (Pamelor) retain much of the effectiveness of their parent molecules, but offer much reduced side effects. I favor the side effect profile of the tricyclics (with the exception of clomipramine - Anafranil) because they don't include apathy, amotivation, extinguished libido, and anorgasmia.


- Scott

 

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