Posted by SLS on July 8, 2006, at 20:46:45
In reply to Re: Any comments regarding sibutramine (Meridia)?, posted by med_empowered on July 8, 2006, at 16:31:27
> Are you trying it for weight loss, or as an AD? For weight loss, I think its considered OK--after a year, most people who stay on the drug lose a bit more weight than those taking a placebo. There are some risks, though, like cardio problems and serotonin syndrome, so do watch for those.
I was thinking of taking sibutramine for its antidepressant properties. The net effect of it and its metabolites is that of triple monoamine uptake inhibition (NE, 5-HT, and DA). It might also act to quickly downregulate NE alpha-2 receptors.
I read an article recently that challenged the assumptions made that sibutramine would be cardiotoxic or produce hypertension. I would still feel more comfortable monitoring blood pressure just the same.
- Scott
poster:SLS
thread:665059
URL: http://www.dr-bob.org/babble/20060701/msgs/665252.html