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Re: STAR*D depressing depression study

Posted by River1924 on July 4, 2006, at 13:58:34

In reply to Level 3 Results of STAR*D announced, posted by Jat on July 4, 2006, at 8:42:28

I saw the article at

It seems summed in this section:

“The results of STAR*D continue to be sobering. By the third wave of the study, the rate of remission continues to be quite low, which underscores the persistence of depression and its resistance to current treatments,” states Robert Freedman, M.D., AJP editor-in-chief.

STAR*D was designed to parallel real-world practice. After the failure of the first one or two medications, often the clinician tries an antidepressant from a different pharmacological class. The antidepressants in Level 3 had pharmacological actions different from those in the previous levels and from each other.

“This finding is particularly relevant to clinical practice because it is based on typical patients,” said Darrel A. Regier, M.D., M.P.H., director of the APA's Division of Research.




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