Posted by blueberry on June 9, 2006, at 7:33:03
For my endogenous melancholic severe depression I am thinking about nortriptyline. None of the ssri's or snri's do any good, actually make things much worse.
I would like details about nortriptyline. I know it is a NE/5HT reuptake inhibitor, and I know about the anticholinergic and antihistimine and side effects and stuff.
I am curious about more details such as...does it function as a 5th2 receptor antagonist? Does it have any effect on 5ht1, such as agonist or antagonist? Any other receptors that it affects? Does it directly or indirectly influence dopamine and if so, how? Any and all details appreciated.
I have slight nervousness and hand jitters from zyprexa, usually between doses but not after a dose. I remember years ago zoloft gave me hand jitters and a tiny bit of nortriptyline made them go away, so I am thinking maybe nortriptyline might be good for anxiety and jitters as well as depression?
poster:blueberry
thread:654765
URL: http://www.dr-bob.org/babble/20060604/msgs/654765.html