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Re: Aimed for sls

Posted by SLS on June 3, 2006, at 15:22:58

In reply to Aimed for sls, posted by willyee on June 3, 2006, at 14:12:07

Hi.

> Hey scott,hope i got ur name right,i keep hearing u mention how u used parnate/desimprimine
> with success.A few quick questions....
>
> Are you still on this combo?

No. It was discontinued because I experienced a manic reaction after six months. I no longer respond to the combination.

> On a scale of one to 10,what number would u give it as far as its value in the combo,meaning if u stopped it.

I felt that I had reached full remission.

> Last isnt it a metablite of imiprimine?

Yes. However, desipramine is selective for norepinephrine whereas imipramine works on both norepinephrine and serotonin. Desipramine would be safer to combine with an MAOI because it is less likely to produce serotonin syndrome. I was able to combine Parnate with nortriptyline without incidence.


- Scott

 

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