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EMSAM Plus Nortriptyline - Possible?

Posted by SFY on May 23, 2006, at 15:58:50

In reply to Re: Maybe this clarifies it a little??? » lymom3, posted by Phillipa on May 23, 2006, at 13:41:01

I know that the EMSAM insert clearly and specifically states that one should not take a tricyclic like Nortriptyline while on it. Similarly, the warnings I got with my last Nort refill proscribe taking any MAOI in tandem with it.

However, there are a number of studies that show few, if any, problems mixing MAOI's and TCA's. This is especially true when one has been on a TCA and then adds an MAOI to it.

I'm currently taking 75 mg. of Nortriptyline and it seems to be doing a good job of keeping me from sinking too deeply into depression. However, it's done nothing for my social anxiety and avoidance, amotivation, anhedonia, and generally blunted emotions. A recent trial with Requip did nothing at all for me.

My next step was to try Emsam because I had a good response to Nardil in the past (but the side effects, esp. the insomnia, became a problem). But I'm wary of having to go off the Nortriptyline and being without any support for my depression until (and if) the EMSAM kicks in. This is especially true as I'm dealing with some current emotional issues that have the potential to send me into a tailspin if my depression comes back full-blown.

I'm just wondering if this is doable. I know I've read about people here taking an MAOI/TCA combo in the past and I'd be interested in any of those experiences as well.


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poster:SFY thread:646882
URL: http://www.dr-bob.org/babble/20060520/msgs/647390.html