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Re: Does Low Dose Seroquel Have Dopamine Antagonism? » TomG

Posted by blueberry on May 14, 2006, at 18:51:52

In reply to Does Low Dose Seroquel Have Dopamine Antagonism?, posted by TomG on May 14, 2006, at 12:12:34

As far as I understand, Seroquel has the lowest amount of dopamine antagonism of them all. And since the amount of antagonism is directly related to the size of the dose, I would guess the amount of antagonism at the doses you are talking about is pretty low. Probably not anywhere near enough to disturb amisulpride.

I have read in studies where they added amisulpride to full doses of other antipsychotics to treat residual negative symptoms and it was generally effective.

I used 25mg amisulpride with 5mg zyprexa and could feel the amisulpride stimulation. Sexual side effects were real bad for me though, so I did not make it past week 2.

Just an opinion and just an educated guess, but I think you should be all set.

Nighty night. Sleep good!


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