Posted by spooly on May 8, 2006, at 18:43:51
In reply to Re: dosage, posted by Jost on May 8, 2006, at 15:17:07
He was originally against it before the pharmaceutical salesman offered him a free round at Pebble Beach where he confirmed, with several colleagues, over a complementary Martini, that it was indeed, effective :)
ahhh...I'm a cynic..sorry.
There were relatively few studies on selegilene til emsam (I know - I scoured the web)and my guess is that not many doctors wanted to open themselves up to litigation to prescribe an "anti-parkinsons" MAOI off-label. They also had little solid evidence.
> I posted this on another thread, but maybe this is a better place to ask.
>
> I'm interested in EMSAM, esp. whether it's a lot more effective than selegiline. My psych doctor originally was against selegiline, on the basis that it wasn't effective; now he's high on EMSAM.
>
> I'm confused, because I could have taken high doses of selegiline, probably, because I was on v. high dose of Parnate without any hypertensive problems. My biggest problem with Parnate was that, rather unusually, it put me to sleep. That's why I needed the high dose--otherwise I was basically asleep all the time.
>
> It wasn't in retrospect a very good idea, but nothing else so far has worked. Except for the cymbalta--which was okay, worth it, but not really great.
>
> I'm just wondering, basically, if selegiline is a rather weak Maoi, why would Emsam be so great-- if the issue of dose is taken out of the picture. And how much of a difference does the larger dose make?
>
> Jost.
poster:spooly
thread:630549
URL: http://www.dr-bob.org/babble/20060504/msgs/641491.html