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reported buprenorphine doses

Posted by pseudoname on April 22, 2006, at 15:36:45

In reply to Emrich on buprenorphine (Lancet 1982), posted by pseudoname on April 22, 2006, at 15:14:50

Various reported total daily doses for buprenorphine in depression treatment, from anecdotal reports & studies.

•DOSE COMPARISONS FROM PDR ENTRY
2 mg sublingual liquid solution would be roughly equivalent to 3 mg tablet
4 mg liquid solution would be roughly equivalent to 6 mg tablet
8 mg liquid solution would be roughly equivalent to 12 mg tablet
16 mg liquid solution would be roughly equivalent to 24 mg tablet


•0.8 mg
EERRIICC on May 3, 2005, at 0:28:02
http://www.dr-bob.org/babble/20050428/msgs/492963.html
Following the results of the "Bodkin study" I tried lower doses of buprenorphine, 0.2-0.8 mg of temgesic, with little effect, should I assume that a higher dose will work better? What is the target dose range for treating depression?

•1.0mg
reefer on April 30, 2005, at 10:07:00
http://www.dr-bob.org/babble/20050428/msgs/491832.html
I can't really answer your question since i'm not socially anxious. But i've been on buprenorphine since November last year. I take between 0.5 and 1.0 mg per day intranasally. This would equal to about 30 - 60 mg Per Oral morphine per day. This drug seems to self regulate in me. I just notice that sometimes a 8 mg Subutex lasts me 1 week and sometimes it lasts me 2 weeks. It seems impossible for me to build up a tolerance for this drug even long term. So i would recommend you try it, it seems to be a very safe opiod. Very mild withdrawal when getting off it completly.

•1.2? mg
Chairman_MAO May 2, 2005
http://www.dr-bob.org/babble/20050428/msgs/492622.html
Have you ever tried buprenorphine on top of your parnate? I suggest getting the Parnate dose up to around 120mg/day and aiming for 0.15-0.3mg buprenorphine tid-qid.

•1.8 mg
Bodkin study (1995)
This comes in small ampules containing 0.3 mg of the drug in 1 ml of aqueous solution. Dosage was titrated according to tolerance and clinical benefit, with a maximum daily dosage of 1.8 mg.

•8 mg
bee happy's dose pooped out 2/11/04:
http://www.dr-bob.org/babble/20040210/msgs/312077.html
"I have been treated for depression with Buprenorphine (2 mgs four times daily) for almost two years. But in the past few months have noticed my concentration has deteriorated..."

•16 mg
Chairman_MAO on May 2, 2005, at 9:48:24
http://www.dr-bob.org/babble/20050428/msgs/492614.html
Oh, my, buprenorphine, definitely! I feel energized yet calm and centered most everywhere I go, and I have never stood up taller than I do now that I am on it. This drug is one of the best things that has every happened to me. Seriously, I try to pray to God every morning in thanks for my daily 16mg of Suboxone--and I'm not even religious! It also works within 1-3 days for many people; no waiting several weeks.

•16-24 mg
http://forum.avantlabs.com/lofiversion/index.php/t16599.html
Chairman_MAO Apr 24 2005, 01:59 PM
IMHO, OCD is best treated with opioids. If I were prescribing for you, I would have you on buprenorphine (target dose 16-24mg suboxone per day or Buprenex intranasal) for the OCD + selegiline 2.5mg b.i.d. + 10-60mg PEA per day for energy, if needed.


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poster:pseudoname thread:635895
URL: http://www.dr-bob.org/babble/20060417/msgs/635901.html