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Re: Amisulpride Sucks So Far.... » SLS

Posted by linkadge on April 9, 2006, at 19:32:51

In reply to Re: Amisulpride Sucks So Far...., posted by SLS on April 9, 2006, at 18:54:07

I wouldn't think there would be latency either. The rational for this drug strange/mixed. It would not need time to desensitize dopamine autoreceptors like perhaps a MAO-B inhibitor. Wasn't it thought to work as dopamine autoreceptor antgonist ?

The other issue is that, it still is an antipsychotic. I think it has strong antagonistic affinity for D3 receptors (which are heavily located in the neucleus accumbens). So the net effect on dopaminergic neurotransmission, I don't know.

Linkadge


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