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Re: Atypical antipsychotics as prophylaxis?

Posted by Caedmon on March 31, 2006, at 8:12:43

In reply to Re: Atypical antipsychotics as prophylaxis?, posted by tygereyes on March 30, 2006, at 20:58:12

I'm not aware of evidence showing that APs can prevent subsequent psychotic episodes. It makes sense, but I don't know.

You'd be balancing possibilities. Do I want to have a lowered odds of psychosis (assuming this can be an outcome)? Or do I want to develop metabolic syndrome X (or possibly EPS)? Kind of tricky.

Prodromal schizophrenia might respond just as well to some behavioral interventions (when not psychotic) that help with increased socialization and so on. Bipolar mania, IMHO, is appropriately treated with APs but prophylactic drugs should be lithium or anticonvulsants whenever possible. So, that kind of narrows things down.

- C


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URL: http://www.dr-bob.org/babble/20060329/msgs/627019.html