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Re: Any more studies done on SSRI/corscrew recepto » linkadge

Posted by yxibow on March 29, 2006, at 0:20:41

In reply to Re: Any more studies done on SSRI/corscrew receptors? » Glydin, posted by linkadge on March 26, 2006, at 20:23:18

> Well this is it, although, I wouldn't call it what I feel is "comfortable".
>
> The SSRI's have not been around long enough. Simply put, we lack long term safety data.

Actually the first drug that could be called an SSRI has been around for 37 years, Clomipramine (Anafranil), a tricyclic with SSRI properties, although only approved in late 1989 in the US. Zimelidine was approved in the early 80s by what is now Astra-Zeneca, and banned eventually due to the rare Guillain-Barré syndrome and other multiple organ issues. It was followed shortly by Prozac (1987) which was derived from studies of Benadryl, which it is related to, among other things. So we have around at least 20 years here and more elsewhere of true SSRI history. I'm not saying we know everything about them but we have had quite a number of patient-years of medication.

 

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