Posted by Tony P on March 25, 2006, at 0:59:21
In reply to Re: Never thought I'd hear this..... » Tony P, posted by SLS on March 24, 2006, at 7:19:02
> Hi Tony,
> How are you doing on the tianeptine? Any side effects? How much are you taking?
I was taking the manufacturer's suggested 12.5 mg 3x/day (12.5 -- weird number -- I suppose they did their first trials with 100 or 50 mg then titrated down by halves). I stopped taking it in order to a) see if it was having a real effect, b) get a new emotional baseline without the Lamictal. I may re-start the tianeptine earlier than I had planned as I am getting fairly depressed fairly fast, and also experiencing some anxiety.
I got an immediate lift from it (which might have been placebo) and felt like it was helping moderately with both depression & anxiety, but I figured the only way to be sure it was doing something real was to stop and restart. The only side-effect I experienced was a slight digestive upset; I felt at times like there was something caught in my throat or I'd eaten too much. I need to lose weight anyway ;)
I wonder if the anxiety today might be Lamictal withdrawal -- it has a long half-life so it's hard to be absolutely sure; I'm going down from 200 mg/day by 50 mg every three days and this is day 4 (my pdoc suggested 50 mg every 2 days) - how does that sound to anyone with experience with this AD?
> Have you ever tried an MAOI or tricyclic?
Never tried an MAOI, was always put off by the potential side-effects and forbidden foods list, and the profile didn't sound right for me -- I don't do well with a lot of NA activation; the newer selective MAO-B ADs like selegeline might be OK.
Tried Elavil (amitriptyline) and Sinequan (doxepin) years ago, Elavil was a bit too activating, Sinequan at 25 mg tid (if memory serves) drove me straight up the wall -- intolerable anxiety around day 7-10.