Posted by yxibow on March 21, 2006, at 21:33:28
In reply to Re: Klonopin adjustment, posted by Talbot on March 21, 2006, at 18:49:21
> If I'm having a real bad day with more stress/anxiety than usual, I notice that if I take my recommended dose, BUT break the pill in half, it seems to work much quicker. I'm assuming this is because it can be metabolized quicker in the GI tract. Would this be similar to as how letting a table dissolve under your tongue seems to work quicker?
>
> Also, by using either method mentioned above, would this alter the half-life of the clonazepam (and make it poop out quicker)?No, the half life is determined by the circulation in the bloodstream. It seems that you, if this is possible, since benzodiazepine tablets are generally not sustained or delayed release (except Restoril and I'm not even sure there, its just a drug delivery shell for messy powder), have possibly altered some sort of release in the binding powder of the medication.
All that is changed, if it isn't a placebo effect, or sheer luck, is the "time to peak plasma level."
( http://www.dr-bob.org/tips/bzd.html )
- J
poster:yxibow
thread:621590
URL: http://www.dr-bob.org/babble/20060315/msgs/623146.html