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Re: Drug Interactions With Grapefruit » fenix

Posted by Larry Hoover on February 26, 2006, at 12:42:38

In reply to Re: Drug Interactions With Grapefruit, posted by fenix on February 25, 2006, at 16:19:49

> > I always wondered why they said no grapefruit juice with meds. Fondly, Phillipa
>
> Yeah, me too and I eventually decided to look up stuff on it. I also did a search on dr-bob.org for "grapefruit" and then I found out that there were already some topics on it from the past.
>
> It fascinates me really; the whole thing with the grapefruit and all. It is just a humble fruit yet it can do some interesting things when you eat it concomitantly with certain medications.

The grapefruit effect is an inhibition of a specific liver enzyme. That same enzyme can also be induced (speeded up) by other meds. One example of that would be St. John's wort. Grapefruit and SJW are on opposite ends of the teeter-totter.

Lar

 

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URL: http://www.dr-bob.org/babble/20060219/msgs/613459.html