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Re: Reward Deficiency Syndrome, Motivation and ADD

Posted by SLS on February 18, 2006, at 7:30:18

In reply to Reward Deficiency Syndrome, Motivation and ADD, posted by psychopharmaddict on February 16, 2006, at 8:41:08

Hi.

Reward deficiency and loss of motivation are two features of my illness too.

My condition looks very much like the deficit syndrome usually associated with the negative symptoms of schizophrenia. It seems to overlap with your description quite a bit. However, I have had brief responses to standard antidepressants as well as stimulants. My best response was to a combination of Parnate + desipramine. I would probably be on those same drugs today if the doctor hadn't discontinued them prematurely. I no longer respond to them.

http://www.biopsychiatry.com/anhedschiz.htm

The main features of my depression are anergia, psychomotor retardation, anhedonia, loss of interest and motivation, impaired cognition and concentration, reduced libido, hyperphagia, and hypersomnia. Because I have experienced several medication-induced manias, it is assumed that my condition is the result of a bipolar diathesis. When I do respond to something, the response lasts for a few days to a week at most. Some drugs have worked episodically for three weeks, but nothing compares to the smooth and consistent remission I achieved with the MAOI + TCA combination.


- Scott

 

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