Posted by 4WD on February 2, 2006, at 21:52:49
In reply to Re: Mifepristone failure? It looks that way. » 4WD, posted by SLS on February 2, 2006, at 8:03:14
> Hi Marsha.
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> > > It has been a week since I took my last dose of mifepristone. I don't feel any better now than I did before the treatment. Damn.
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> > I'm so sorry, Scott. Will you try the EMSAM patch when it comes out?
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> I guess I'm not that attracted to EmSam because I didn't respond to oral selegiline 30mg 15 years ago. I currently take Parnate 80mg and have been as high as 150mg. I guess I am guilty as anyone else here of characterizing drugs based upon a simplistic use of what little data there are on them. I can't see what selegiline would do that Parnate would not. I won't cross EmSam off my list, but there may be things I would like to try first. I do remember, however, Dennis Murphy, MD, telling me that selegiline would be worth another try because I did respond to clorgyline. Both drugs are propargyl derivatives. It is very disconcerting that there are so few things in psychopharmacology that are well understood or that one can count on except that these drugs usually produce undesirable side effects.
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> - ScottYeah nothing is certain except, death, taxes and side effects.
My neurologist admitted that they know next to nothing about how the brain works or how and why ADs work or don't. When I asked him "what happens in the brain while a person is asleep that would make them wake up scared?" His reply "If I knew that, I'd be in Switzerland." At least he was honest.
I'm starting a trial of imipramine myself (as soon as the pharmacy can order it). It worked in 1986, maybe it'll work now. Never give up. Even when (as you so eloquently said in another thread) you have to give up for a while and give in to it.
Maybe transdermal selegiline would work differently. I know that transdermal hormones like estrogen and progesterone can have different or better effects when used transdermally instead of orally. And remember all the posts about how Nardil absorbed in the intestine works better than Nardil absorbed in the stomach.
Marsha
poster:4WD
thread:603490
URL: http://www.dr-bob.org/babble/20060129/msgs/605663.html