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Unopposed Beta-Blockade

Posted by mike99 on January 10, 2006, at 11:13:20

In reply to Re: Beta Blocker (Re: Cardiovascular Stimulation, posted by mike99 on January 10, 2006, at 11:00:16


I've heard of many people taking beta-blockers to counter the cardiovascular activation of stimulants.

However, in a prior post a babbler strongly recommended against this as it could lead to "unopposed beta-blockade"-- meaning that the alpha receptors would be overstimulated in relation to the beta receptors (beta blocked but not alpha)-- leading to tachycardia, high-blood pressure...and so that a mixed alpha/beta antagonist such as labetalol or carvedilol should be used to counter a stimulant.

I believe I recall hearing this in a pharmacology class also. Can anyone provide more information on this?


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poster:mike99 thread:595951
URL: http://www.dr-bob.org/babble/20060108/msgs/597551.html