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Re: Cymbalta Insomnia- Trazedone?

Posted by Dawnie on December 30, 2005, at 23:08:32

In reply to Re: Cymbalta Insomnia- Trazedone? » flipsactown, posted by yxibow on December 28, 2005, at 22:57:19

> > I have been on 60mg Cymbalta for 7 weeks and have been experiencing insomnia for which I take 100mg Trazodone. I sleep very well on Traz getting quality REM sleep. However, I am male and also experience anorgasmia with Traz.
>
> I'm a natural insomniac so I can't say that Cymbalta has contributed significantly to it like Effexor did years ago when I tried it.
>
> >I tried taking Remeron which is also very sedating, but Remeron gives me quite an appetite and I pack on the pounds.
>
> Definately -- I'm just pushing off 40% of it in the gym.
>
> >I hope the sexual side effect of Trazodone will subside in time.
>
> It probably will -- but one thing, and I assume your doctor knows, is that Trazodone and Cymbalta are both metabolized by P450 CYP2D6, which means there is a slight potential for drug-drug interactions. The anorgasmia is probably more due to the Trazodone, but could also be due to the combination.
>
> Decreased libido was reported in 1.3% of the outpatient community in Trazodone tests. Of course then there is "the problem" with Trazodone to watch for in relation to this -- priapism. Occurs more often than not, not to scare you (I experienced it mildly mostly about once every few months but continued to take the drug for a while) -- although if you're younger, you're probably likely not to be in too much danger of such a situation.
Are you aware othe dangers of men taking Trazedone. A new psychiatrist (one covered by our insurance) put my son on it a few years ago (along with a number of other med changes) and when he started getting extremely manic we went back to our old psychiatrist. He took him off the Trazedone immediately. Apparently a side affect in men is a painful erection that wont go away and often needs surgery. The late Freddie Prinze had this happen to him. I would ask your doc about this. Ask him about Ambien instead.


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poster:Dawnie thread:589545
URL: http://www.dr-bob.org/babble/20051221/msgs/593634.html