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Re: Why/how do noradrenergic drugs increase anxiety?

Posted by jamestheyonger on December 25, 2005, at 14:44:47

In reply to Why/how do noradrenergic drugs increase anxiety?, posted by Racer on December 24, 2005, at 21:50:56

Noradrenergic AD's are my mainstay, the SSRI's just do not work for me. My depression tends to be issues of motivation and drive and less mood, which fits the noradrenergic model of depression as we understand it today. Noradrenergic AD's work so well I do not have big problems with anxiety. High dose Effexor and Wellbrutin don't bother me too much in the anxiety area though Effexor, after 10 years, had a major effect on BP.

What is needed for me is a counter agent. 15 years ago all we had was TCA's and the ones that were noradrenergic (Doxipin) were also very sedating. A one pill solution. Once the TCA's
pooped out I found a sedating AD at night with Effexor smoothed things out. Either Doxipin or Remeron. Now I am on Wellbrutin and Remeron.
I also use Atavin as needed, partly for GAD and partly for the AD induced anxiety. When the anxiety is more physical Inderal works quite well.

j


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URL: http://www.dr-bob.org/babble/20051221/msgs/592096.html