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Re: A desperate alternative

Posted by med_empowered on November 28, 2005, at 8:26:34

In reply to Re: A desperate alternative » Tepiaca, posted by ace on November 28, 2005, at 8:00:29

hey! sorry you're having a rough time. Trust me, though--whatever you're feeling, odds are someone here at the board has felt it, too.

Anyway, like one poster said, it seems like something like tianeptine would be ideal to create that kind of feeling. My guess would be that you could create something kind of similar if you used an SSRI with a serotonin antagonist...docs like APs for this, but it seems like BuSpar would work just fine, if you can tolerate it. It seems like for some people adding BuSpar makes SSRIs more tolerable (less sexual dysfunction, faster response, better response, less akathisia and anxiety). My wild, UN-educated guess would be that BuSpar's serotonin antagonism, combined with *mild* D2 antagonist/agonist action helps counteract the apathy you see with SSRIs by allowing you the benefits of increased serotonin (from the SSRI) while also keeping the serotonin system going at the usual pace, and also preventing too much dampening of the dopamine end of things. Like I said though, thats just a guess. My own experiences with BuSpar were so-so, but I took it for anxiety.


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