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opioids and sleeplessness

Posted by pseudoname on November 21, 2005, at 22:13:08

Does anybody else find opioids awakening? The past 4 times I've tried buprenorphine I've found that although I'm tired & sleepy & lying in bed with my eyes closed, I'm wakeful in my head.

I see in the literatue that opioids reduce REM and that mu agonists especially do this (bupe has mu agonists). Also, long-term use leads to insomnia. But these aren't quite my situation.

I also see that "Oddly enough, little is known about the effects on sleep of commonly administered analgesics" including opioids.

Anybody else get woke up by opioids?


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poster:pseudoname thread:581069
URL: http://www.dr-bob.org/babble/20051119/msgs/581069.html