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Re: If Lithium makes me *more* anxious... linkadge

Posted by cache-monkey on November 12, 2005, at 19:45:33

In reply to Re: If Lithium makes me *more* anxious..., posted by linkadge on November 12, 2005, at 16:05:44

Hi Link,

The anxiety actually was worse at higher levels of Lithium (up to 600 at some point). Interesting re: the serotonin enhancement. Makes me wonder whether an SSRI is the way to go. I guess I got decent results with Celexa many years ago, so I'm holding out hope that the serotonin actions of Li are different than an SSRI. But if the Lexapro doesn't work out, I'll see if my pdoc is open to Mirapex or something along those lines.


> Lithium is a 5-ht1b autoreceptor antagonist. It enhances serotonin release in certain areas of the brain.
> Anxiety with lithium is fairly uncommon. The drug can cause a degree of akathesia which may manifest itself as anxiety.
> 225mg is a very low dose. Less than 1/3 of what most people use for bipolar disorder.
> I would consider the use of other agents, esp if you have tried higher doses of lithium.
> Linkadge




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