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Re: parnate and fludrocortisone blackcat23

Posted by fires on November 10, 2005, at 14:21:18

In reply to Re: parnate and fludrocortisone, posted by blackcat23 on November 9, 2005, at 21:46:51

> I'm taking .1 mg a day of flodrocortisone. In addition, I take 50 mg of Cytomel (a thyroid supplement), 200 mg of Lamictal. I never had the OH until the Parnate, of course. I've been taking it for a little over a week at 30 mg. I ramped up my dose to 30 mg. quickly, so am wondering if that contributed to the extreme OH as well.
> Anyway, I'm curious about the other meds you mentioned. I'll research them as well-- do you know if there are advantages to the others over the flodrocortisone?
> Thanks for your response. I really appreciate it!

I think that increasing your dose of Parnate quickly probably made the OH worse. When I was increasing my dose fairly rapidly toward 90 mg, I had a BP of about 70/45 while in bed. I had quite a few episodes of "going blind and deaf" about 30 seconds to 1 min. after standing up -- yet I never fainted.

Nurses didn't believe me at first, because they would take my BP right after standing. I finally told them to wait 30 seconds before taking my BP -- then they did get low readings.

The use of Reglan for OH is very off-label, but since it worked I was on it for about 15 years.

I take 0.1 mg of Florinef x2 per day, for another condition. I didn't know that it was used for Parnate OH.

I know that Florinef is generally considered safe for long term use, and that it has few side effects. Reglan can cause severe side effects in some people. I couldn't find my reference for theuse of Midodrine for OH.

I also take 200mg of Lamictal per day now, along with 300 mg of Wellbutrin and 8 mg of Rozerem and .5 mg of clonazepam (instead of Parnate).

Good Luck




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