Posted by jerrympls on October 31, 2005, at 1:01:48
In reply to Treatment resistant depression, posted by Girlnterrupted on October 30, 2005, at 9:57:54
This seems to happen more and more - or more people are talking about it: where the very first AD they were on helped them tremendously and either a) they decide they're back on track and stop the med or b) the doc gets a "great idea" and screws with the meds. Then depression returns and the person's depression becomes treatment resistant - even to the very first med that helped so much.
This happened to me too. I was on Trazodone 75mg at night (14 years ago). Iin 2 weeks I was perfect - NORMAL! After 3 months on it my doc said I was "back on track" and could stop it. Well, I stopped it and here I am 14 years later searching for a cure - not responding to conventional treatments. Now it's like I have to have a med to help me be social and laugh, a med to help me focus and be motivated, a med to help me relax and not worry so much and a med to put me to sleep each night.
I digress - but what is this phenomena of responding very well to the first med and then not repsonding to any meds following the discontinuation of the first med? Does the brain's chemistry become intelligent to future invading mood boosters? Do you think perhaps the brain fights against later treatments somehow? Figures them out and blocks their effects via downregulation, etc?
curious..
poster:jerrympls
thread:573337
URL: http://www.dr-bob.org/babble/20051024/msgs/573648.html